Study of visual information processing using retinal organotypic culture system
نویسندگان
چکیده
منابع مشابه
Effects of bevacizumab (Avastin) on retinal cells in organotypic culture.
PURPOSE Repetitive intravitreal injections of bevacizumab are a successful treatment option for exudative age-related macular degeneration (AMD). The aim of this study was to evaluate the toxicity of bevacizumab in the adult mammalian neurosensory retina in culture. METHODS Adult porcine neurosensory retinas were cultured adjoined to the retinal pigment epithelium-choroid layer (retina-RPE-ch...
متن کاملFluoroGold-Labeled Organotypic Retinal Explant Culture for Neurotoxicity Screening Studies
Preclinical toxicity screening of the new retinal compounds is an absolute requirement in the pathway of further drug development. Since retinal neuron cultivation and in vivo studies are relatively expensive and time consuming, we aimed to create a fast and reproducible ex vivo system for retinal toxicity screening. For this purpose, we used rat retinal explant culture that was retrogradely la...
متن کاملa study on construction of iranian life tables: the case study of modified brass logit system
چکیده ندارد.
15 صفحه اولIn vivo-like Organotypic Murine Retinal Wholemount Culture
Targeted ablations of genes and analysis of animal models is the classical strategy for enrolling specific retinal gene function. However, transgenic, retina-specific or conditional knockout mouse models often display early lethality or suffer from severe malformations, preventing an analysis beyond embryonic or early postnatal stages. Primary cell culture is an alternative to investigate the e...
متن کاملTime-Lapse Retinal Ganglion Cell Dendritic Field Degeneration Imaged in Organotypic Retinal Explant Culture
PURPOSE To develop an ex vivo organotypic retinal explant culture system suitable for multiple time-point imaging of retinal ganglion cell (RGC) dendritic arbors over a period of 1 week, and capable of detecting dendrite neuroprotection conferred by experimental treatments. METHODS Thy1-YFP mouse retinas were explanted and maintained in organotypic culture. Retinal ganglion cell dendritic arb...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Life Support Engineering
سال: 2005
ISSN: 1341-9455,1884-5827
DOI: 10.5136/lifesupport.17.supplement_73